Emergency Medical Technician (EMT) Intermediate Practice Exam

Where do signs of anaphylaxis typically manifest first in the body?

1. Digestive system

2. Respiratory system

3. Skin

4. Nervous system

The correct answer is: Skin

Signs of anaphylaxis typically manifest first in the skin, making this the correct answer. Anaphylaxis is a severe allergic reaction that can occur rapidly after exposure to an allergen. One of the hallmark early symptoms of anaphylaxis is the appearance of hives, itching, and flushing of the skin. These symptoms are a result of the body's immune response to the allergen, leading to the release of histamines and other chemicals that affect the skin. While other systems can become involved as the reaction progresses, the skin is often the first area to show signs of anaphylaxis. This early response can include angioedema, which is swelling beneath the skin, particularly in areas like the face and lips. The digestive system may also show symptoms, such as nausea, vomiting, or abdominal cramping, but those typically follow the initial signs in the skin. The respiratory system can experience symptoms like wheezing and difficulty breathing, but again, these signs generally develop after the initial cutaneous symptoms. The nervous system is less commonly involved in the early phases; it may show symptoms if the reaction continues to escalate and affects overall bodily function. Thus, identifying the early skin manifestations is crucial for rapid recognition and treatment of anaphylaxis.